Chapter 2:
Organic Germanium Compounds
And What They Do
Therapeutic
Properties Of Organic Germanium
Twenty years have passed
since the original synthesis
of an organic Germanium
compound. During that period,
organic Germanium has been
used clinically in many
parts of the world to treat
a wide spectrum of illnesses,
and has been the subject
of extensive research in
many disciplines: pathology,
biochemistry, pharmacology,
immunology, oncology and
neurochemistry.
Organic Germanium has been
used in a broad spectrum
of regimes - on its own,
with diet and stress counselling,
and as a drug in cancer
trials, in conjunction with
chemotherapy, radiation
therapy and surgery. Drawing
these sources of information
together gives quite a solid
overview of the fundamental
aspects of organic Germanium.
The safety of organic Germanium
has been well-documented,
as has its health promoting
effects in many diseases,
including cancer and arthritis.
Case histories, and in some
instances, clinical trials,
have documented Organic
Germanium's therapeutic
effects in treating the
following conditions:
Rheumatoid Arthritis And
Rheumatism
Cancer - Colon, Prostate,
Breast, Lung, Ovarian, Cervical
Leukemia
Asthma
Diabetes
Malaria
Senile Osteoporosis
Mental Disorders -Depressive
Psychoses, Schizophrenia,
Pain
Digestive Disorders -Gastritis,
Ulcers
Influenza
Cardiac Disorders - Angina,
Hypertension, Arteriosclerosis,
Apoplexy, Cardiac Infarction
Circulatory Disturbances
- Raynaud's Disease,
Parkinson's Disease
Cerebral Sclerosis
Skin Eruptions - Warts,
Corns, Eczemas, Burns, Herpes
Epilepsy
Old-Age Infirmities
Amyloidosis
Myelo-Optico-Neuropathy
Eye Diseases - Glaucoma,
Black Cataracts, Detached
Retinas, Inflammation Of
The Retina And Optic Nerves,
Behcet's Disease
Double-blind, controlled
studies have been carried
out on several of the above
conditions, particularly
in cancer. Although individual
case histories are not in
themselves sufficient proof
to the scientist of a substance's
effectiveness, positive
results obtained with organic
Germanium over many years
with large numbers of patients
with many disorders, certainly
provides a basis for more
rigorous testing of organic
Germanium's therapeutic
properties.
Organic Germanium Compounds
Ge-132: Carboxyethyl Germanium
Sesquioxide
The organic germanium compound
carboxyethyl germanium sesquioxide
or Ge-132 was synthesized
by Asai's group in 1967.
Details of its synthesis
and crystal structure were
published in 1976 in the
Journal of the American
Chemical Society (108).
The synthesis is carried
out by the hydrolysis of
an organogermanium trichloride.
Of the four Germanium electrons,
three are bonded with an
oxygen atom; the fourth
electron is a free radical.
A regular symmetrical lattice
network is formed, as shown
in diagram . The biochemical
significance of this crystalline
structure will become apparent,
in discussing organic Germanium's
ability to scavenge free
radicals, protect against
radiation, enrich the body's
oxygen supply and rid the
body of heavy metals.
Sanumgerman
Sanumgerman, chemical name,
lactate-citrate-germanate,
is an organic Germanium
product manufactured by
Sanum-Kehlbeck in West Germany.
This company has had a close
association with Dr. Asai,
and has been developing
and researching formulations
of organic Germanium for
more than a decade.
The development of the
organic Germanium compound
Sanumgerman grew out of
the cancer research findings
of oncologist Dr.Seeger
of the Robert-Koch Institute,
Berlin dating from 1938.
Dr. Seeger had been investigating
electro-chemical metabolic
processes at the cellular
level which caused normal
cells to become cancerous.
In his search for electronic
acceptors which would cause
cancer cells to revert to
normal, he tested Dr. Asai's
organic Germanium compound,
which he found to be highly
effective.
The close relationship
between Dr. Seeger and the
founder of the firm Sanum-Kehlbeck,
Heinrich Kehlbeck, deepened,
with extensive research
aimed at developing an effective
organic Germanium at Sanum's
laboratories. After many
years and variations of
organic ligands, the compound
germanium-lactate-citrate
was found to be optimum.
Sanumgerman has been extensively
used by practitioners throughout
Europe for about 10 years.
The safety and research
data compare and confirm
the results obtained with
Ge-132, although no studies
comparing the two formulations
have as yet been done.
Spirogermanium
Spirogermanium, synthesized
by Rice et al (83), is an
organic germanium compound,
belonging to a class of
azaspirane compounds. Spirogermanium
has been evaluated for its
anticancer and antiarthritic
activity by Smith Kline
& French Laboratories.
Its patent rights are owned
by Unimed Inc., USA. The
research data on this organic
Germanium's mode of action
corroborate results obtained
with Ge-132 and Sanumgerman;
however, this compound has
been developed and treated
as a drug rather than as
a nutritional supplement,
and exhibits some transient
neurological toxicity. Spirogermanium
is not currently available
on the market.
documenting
the scientific basis for
Dr. Asai's originally intuitive
ideas of organic Germanium's
therapeutic properties.
